depends on terrain
open fields usually requires me to use overwatch with a platoon of inf. with Jav missile launchers to counter tank threats, everyone else covers the open terrain in hunt, if threat is high and contact is likely, all squads are dismounted, but strykers lead the advance as they're invulnerable to small arms an usually the slat armor helps against the RPG threat.
Here's when things get really tricky.
Urban settings...
The problem here is this: slat armor protects the stryker from most RPGs but the slat armor doesnt cover the entire vehicle. thus, if an RPG team is in a position where it can shoot DOWNWARD and avoid the slat armor, even light RPGs can kill a stryker, so, the doctrine is this:
Infantry leads by using bounding movements, usually platoon watches over platoon and at the same time secure both sides of the road the strykers are to move down, and at the same time watching for IEDs.
But this is only when I need to get the strykers into more "favorable" terrain. otherwise, if its simply house to house battle, I don't even bring them into the city unless the Infantry is running low on ammo, cause if I carelessly get a stryker blown up, then I loose the ammo inside too, which is useful in drawn out battles.
if there is a break in cover within the city, then smoke from the strikers help provide concelement