Occasionally, if you have a crash of your computer, it will leave CMH in a state where it can't run anymore.
To recover from this, you need to do one of two things. Either:
a. Run CMH from a command prompt with the reset-state option
DOS> cmh.exe reset-state
OSX> ./cmh.app reset-state
or
b. Delete CMH's AppState.txt file
At the top of the log window (Options->Show Log Window) CMH tells you where the log file is stored - the AppState.txt file is in the same place. If you can't access the log file, you will need to search your disk for AppState.txt.