I run Vista 64, with dual-monitors.
Neither the main game executable, nor the editor will launch (though the un-installer will).
I have tried running it as Administrator and it makes no difference.
There is no error message of any kind, when I click on either the game or the editor the cursor (very) brielfy flickers (to a circle then back to a pointer) and nothing else happens. I can see no left-over process running either.
I bought the game yesterday, installed it without any problems, but encountered this non-launching issue immediately thereafter (in fact, even from the installer).