I put a new motherboard in a couple of weeks ago, but I play CM daily, no problems. I usually leave my system running. Today, I shut it down before leaving for work. I came home, started up the system, will not run CM.
I tried rebooting, and on one of the reboots, I got a "cannot start 3d graphics' window, only appered once.
I did try to run it off the CD, no luck